Researchers illuminate neurotransmitter transport using X-ray crystallography and molecular simulations

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Researchers illuminate neurotransmitter transport using X-ray crystallography and molecular simulations

Scientists from the MIPT Research Center for Molecular Mechanisms of Aging and Age-Related Diseases have joined forces with their colleagues from Jülich Research Center, Germany, and uncovered how sodium ions drive glutamate transport in the central nervous system. Glutamate is the most important excitatory neurotransmitter and is actively removed from the synaptic cleft between neurons by specialized transport proteins called excitatory amino acid transporters (EAATs). The findings are reported in Science Advances.

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