Results of comprehensive SARS-CoV-2 animal model study published

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Results of comprehensive SARS-CoV-2 animal model study published

Scientists at Texas Biomedical Research Institute (Texas Biomed) and Southwest National Primate Research Center (SNPRC) published their findings regarding a comprehensive animal model study of SARS-CoV-2 in the peer-reviewed journal Nature Microbiology. These findings were originally posted online in BioRxiv in June of 2020. The study evaluated three nonhuman primate (NHP) species (Indian rhesus macaques, African baboons and new-world origin common marmosets) and young and old animals, to determine susceptibility to the SARS-CoV-2 virus and the development of COVID-19 disease. Over the course of the study, the macaque and baboon models showed significant promise as animal models for COVID-19 disease studies moving forward. Based on outcomes, the researchers recommended use of the macaque as a model to help develop vaccines, while the baboon showed greater disease development, making it a potential option for evaluating anti-viral therapeutics and co-morbidities, such as understanding the connection between COVID-19 and diabetes or COVID-19 and heart disease.

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