New reports of Ebola in Guinea are causing anxiety given the history of the West Africa outbreak of 2014-2016. This was the largest Ebola outbreak reported to date—28,000 cases were recorded, including 11,000 deaths. It originated in Guinea and then spread to Sierra Leone and Liberia. The confirmed cases this time have been reported from the southeast of Guinea about 800km by road from the capital, Conakry, but only about 100km from various border points with Liberia and Côte d’Ivoire. The concern is that the virus could spread to other locations in Guinea as well as neighboring countries if it is not rapidly contained. Jacqueline Weyer answers questions about the latest outbreak.