3-D holographic microscopy powered by deep-learning deciphers cancer immunotherapy

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3-D holographic microscopy powered by deep-learning deciphers cancer immunotherapy

Live tracking and analyzing of the dynamics of chimeric antigen receptor (CAR) T-cells targeting cancer cells can open new avenues for the development of cancer immunotherapy. However, imaging via conventional microscopy approaches can result in cellular damage, and assessments of cell-to-cell interactions are extremely difficult and labor-intensive. When researchers applied deep learning and 3-D holographic microscopy to the task, however, they not only avoided these difficultues but found that AI was better at it than humans were.

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