Discovery offers potential for stripping tumors of T cell protection

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Discovery offers potential for stripping tumors of T cell protection

Immunologists at St. Jude Children’s Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system. Surprisingly, the mechanism does not affect regulatory T cell function outside the tumor and may therefore limit the immune-associated toxicities of targeting regulatory T cells.

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