Single-cell imaging to completely define tumor micro-metabolic state

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Single-cell imaging to completely define tumor micro-metabolic state

Many big pharma companies were able to roll out vaccines against SARS-CoV-2 in record time by retooling their existing experimental mRNA gene therapies to carry a new payload. Whereas these cancer vaccines originally coded a single RNA molecule neoantigen concatemer that could be optimally presented on specific HLA receptors to enhance CD8+ T cell anti-tumor responses, they can now deliver optimized versions of the spike protein receptor binding domain to arouse production of protective neutralizing antibodies.

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