Using cannabis for relief from migraine headache may be associated with developing “rebound” headache, or medication overuse headache, which occurs when pain medication is overused by patients who have an underlying primary headache disorder such as migraine, according to a preliminary study released today March 1, 2021, that will be presented at the American Academy of Neurology’s 73rd Annual Meeting being held virtually April 17 to 22, 2021.