Structure and dynamics of key receptor in migraine pain determined, paving way for better treatment options

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Structure and dynamics of key receptor in migraine pain determined, paving way for better treatment options

A research team with members from Monash University, the ARC Centre for Cryo-electron Microscopy of Membrane Proteins, the University of Tokyo and the University of Otago have determined the shape and kinetics of an important cell surface (membrane) receptor called calcitonin gene-related peptide (CGRP), which has long been implicated in migraine. The work has been published in the journal Science.

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