As integral members of stroke treatment teams, nurses coordinate patient assessment and collaborate care among multiple health care professionals to facilitate the best possible outcomes for patients with acute ischemic stroke. Nurses also advocate for patients and their caregivers to ensure they receive appropriate information and education to successfully navigate phases of treatment in the hospital and after discharge. A series of three new Scientific Statements, “Care of the Patient With Acute Ischemic Stroke,” from the American Heart Association, published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association, provide the latest evidence-based guidance for nurses working in a variety of stroke care settings, including hyperacute settings, emergency departments, intensive care units and stroke care units.