Antiphospholipid syndrome breakthrough: Cell-surface targets identified, opening path to therapies

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Antiphospholipid syndrome breakthrough: Cell-surface targets identified, opening path to therapies

A team of researchers affiliated with multiple institutions in Germany and the U.S. have found a cell-surface target for autoantibodies targeting phospholipids (aPL) that contribute to antiphospholipid syndrome (APS). In their paper published in the journal Science, the group describes how they used mouse models of APS with aPL-induced fetal loss and thrombosis to study the connection between the factors that contribute to APS.

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