RNA editing protein ADAR1 protects telomeres and supports proliferation in cancer cells
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12 March 2021RNA editing protein ADAR1 protects telomeres and supports proliferation in cancer cells
Scientists at The Wistar Institute identified a new function of ADAR1, a protein responsible for RNA editing, discovering that the ADAR1p110 isoform regulates genome stability at chromosome ends and is required for continued proliferation of cancer cells. These findings, reported in Nature Communications, reveal an additional oncogenic function of ADAR1 and reaffirm its potential as a therapeutic target in cancer.
