Mapping the cerebral vascular network in human patients, at unprecedented scales: This tour de force has been achieved by the French laboratory Physics for Medicine Paris (ESPCI Paris-PSL, Inserm, CNRS). In a study published on the front page of Nature Biomedical Engineering, the research team details its method—ultrasound localization microscopy, which combines ultrafast sonography and contrast agents. The researchers have addressed several technical challenges to apply the method to human patients. The resulting images are spectacular, and carry vast amounts of information on cerebral blood flows as well as their dynamics. Ultrasound localization microscopy opens new horizons for a better understanding and an earlier diagnosis of cerebrovascular diseases such as stroke or aneurysm, and neurodegenerative disorders like Alzheimer’s disease.