Inhibition of proteins activated by nitric oxide reverses aortic aneurysm in Marfan syndrome

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Inhibition of proteins activated by nitric oxide reverses aortic aneurysm in Marfan syndrome

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Centro de Biología Molecular Severo Ochoa (CBM-CSIC-UAM) have discovered that the nitric oxide (NO) pathway is overactivated in the aortas of mice and patients with Marfan Syndrome and that the activity of this pathway causes the aortic aneurysms that characterize this disease.

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