A team of researchers affiliated with institutions in the U.S., Cambodia and France has found an association between antibody afucosylated immunoglobulin levels in the blood and the severity of dengue—and possibly COVID-19. In their paper published in the journal Science, the group describes their study of the antibodies and what they learned about them. Ruklanthi de Alwis and Eng Eong Ooi with the Duke-NUS Medical School in Singapore have published a Perspectives piece in the same journal issue outlining prior work involved in studying the antibody Fc domain and the work done by the team in this new effort.