Targeted therapy pralsetinib safely effectively treats lung and thyroid cancers with RET alterations

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10 June 2021
Seven days in medicine: 2-8 June 2021
10 June 2021

Targeted therapy pralsetinib safely effectively treats lung and thyroid cancers with RET alterations

Results from the multi-cohort Phase I/II ARROW clinical trial, conducted by The University of Texas MD Anderson Cancer Center researchers, showed that a once-daily dose of pralsetinib, a highly selective RET inhibitor, was safe and effective in treating patients with advanced RET fusion-positive non-small cell lung cancer (NSCLC) and RET-altered thyroid cancer. The findings for each cohort were published today in The Lancet Oncology and The Lancet Diabetes & Endocrinology, respectively.

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