Antibiotic Novobiocin found to kill tumor cells with DNA-repair glitch
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17 June 2021Antibiotic Novobiocin found to kill tumor cells with DNA-repair glitch
An antibiotic developed in the 1950s and largely supplanted by newer drugs, effectively targets and kills cancer cells with a common genetic defect, laboratory research by Dana-Farber Cancer Institute scientists shows. The findings have spurred investigators to open a clinical trial of the drug, novobiocin, for patients whose tumors carry the abnormality.
