Drug-induced liver injury (DILI) is an adverse reaction to ingesting a drug, which can appear both in developmental stages, in their clinical use and even after being approved as a drug. It is the main cause of acute liver failure in Europe and the United States, and its incidence has increased as a result of the polypharmacy that goes hand in hand with the increased lifespan of the population, and from the prolonged use of parapharmacy or herbal products.