CRISPR-Cas13 technique targets proteins causing ALS and Huntington’s disease in the mouse nervous system

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CRISPR-Cas13 technique targets proteins causing ALS and Huntington’s disease in the mouse nervous system

A single genetic mutation can have profound consequences, as demonstrated in neurodegenerative diseases such as amyotrophic lateral sclerosis or Huntington’s disease. A new study by University of Illinois Urbana-Champaign researchers used a targeted CRISPR technique in the central nervous systems of mice to turn off production of mutant proteins that can cause ALS and Huntington’s disease.

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