The return of consciousness after traumatic brain injury (TBI) remains something of a mystery for scientists and is not easy to predict. A series of recently published studies by researchers in the Department of Neurosurgery at the Renaissance School of Medicine at Stony Brook University has found that by using technologies to monitor brain functions after TBI, scientists may be able to better predict who will “wake up” after TBI and what brain circuits to target to potentially treat disorders of consciousness.