Targeting ‘cell clustering’ by gene deletion reduces drug resistance

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Targeting ‘cell clustering’ by gene deletion reduces drug resistance

A recent study that shows manipulating and deleting a specific gene (AMN1) from yeast could provide a foundation for a new approach to combatting drug resistance when treating microbial infections or cancer. Led by Gábor Balázsi, Ph.D., of Stony Brook University, and published in Communications Biology, the study centers on disassembling cell clusters that can form an added barrier of drug resistance in the disease process.

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