Signal detection theory may be useful for characterizing cognitive fatigue in multiple sclerosis patients

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Signal detection theory may be useful for characterizing cognitive fatigue in multiple sclerosis patients

Using signal detection theory, Kessler Foundation researchers have furthered their understanding of the mechanisms of cognitive fatigue in a recent neuroimaging study comparing participants with multiple sclerosis (MS) and controls. Researchers found an association between signal detection theory metrics, subjective “state” fatigue, and brain activation patterns in both groups. The MS group showed greater effects of fatigue as evidenced by their response bias patterns.

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