The structure of protein RAF1 revealed: A key step in the development of new drugs against lung cancer

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The structure of protein RAF1 revealed: A key step in the development of new drugs against lung cancer

One of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes—genes that cause cancer when mutated—are responsible for a quarter of all human cancers, including the three tumor types with the highest mortality rates: lung adenocarcinoma, colorectal carcinoma and pancreatic ductal adenocarcinoma.

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