Motivation-pleasure and expression are two latent factors underlying negative symptoms of schizophrenia patients

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Motivation-pleasure and expression are two latent factors underlying negative symptoms of schizophrenia patients

Negative symptoms such as reduced ability to experience of pleasure, lack of motivation and diminished ability to express emotional responses for relevant social interaction are strongly correlated with clinical and functional outcomes of schizophrenia. However, these symptoms usually respond poorly to conventional treatment. It is still not clearly known for the origins, mechanisms and factor structure of negative symptoms.

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