Spacing COVID-19 vaccine doses has benefits, but longer-term outcomes depend on robust immunity

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Spacing COVID-19 vaccine doses has benefits, but longer-term outcomes depend on robust immunity

Delaying second doses of COVID-19 vaccines should reduce case numbers in the near term. But the longer-term case burden and the potential for evolution of viral “escape” from immunity will depend on the robustness of immune responses generated by natural infections and one or two vaccine doses, according to a Princeton University and McGill University study published March 9 in the journal Science.

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